AOD-9604 vs Semaglutide
Well Studied vs FDA Approved
compatible Complementary weight loss mechanisms through different pathways.
Molecular Data
AOD-9604 Semaglutide
Weight 1,815.1 Da 4,113.64 Da
Half-life 3-4 minutes ~7 days (168 hours)
Chain 17 amino acids 31 amino acids
Type Modified hGH C-terminal fragment GLP-1 receptor agonist
Key Benefits
AOD-9604
01 Targets fat loss through selective lipolysis
02 Avoids growth hormone side effects
03 No effect on blood glucose or insulin
04 Does not increase IGF-1 levels
05 Metabolically safer than full hGH
06 Emerging cartilage repair potential
Semaglutide
01 15-20% average body weight reduction
02 Established cardiovascular protection
03 Convenient once-weekly dosing options
04 Comprehensive safety data from extensive trials
05 Flexible injectable and oral formulations
Dosing Protocols
AOD-9604
250-500mcg / Once daily
Fat loss - Standard 250-300mcg Once daily (morning, fasted)
Enhanced fat loss 400-500mcg Once daily (morning, fasted)
Joint support 250mcg Once daily
Conservative start 200mcg Once daily
Semaglutide
0.25mg starting, titrate to 1-2.4mg weekly / Once weekly (same day each week)
Weight Loss Initiation 0.25mg Weekly x 4 weeks, then increase
Weight Loss Maintenance 2.4mg Weekly (after 16-week titration)
Diabetes Management 0.5-1mg Weekly
Cardiovascular Protection 0.5-1mg Weekly
Tolerability-Based 0.25-2.4mg Weekly (individualized)
Side Effects
AOD-9604
Generally well-tolerated in clinical trials
Mild injection site reactions possible
No reported effects on blood glucose or insulin
Semaglutide
Nausea
Diarrhea
Vomiting
Constipation
Abdominal pain
Contraindications
Pregnancy or breastfeeding
WADA prohibited - athletes subject to testing must avoid
Personal or family history of medullary thyroid cancer
Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
Pregnancy or breastfeeding
History of pancreatitis
Research Evidence
AOD-9604 Semaglutide
Status Well Studied FDA Approved
References 4 studies 6 studies
FDA Approved No Yes
This comparison is for educational and research purposes only. Consult a healthcare professional before use.