CJC-1295 (without DAC) vs GHK-Cu
Well Studied vs Well Studied
synergistic Mechanism-based · 47% CJC-1295 (without DAC) and GHK-Cu work through complementary pathways. Growth hormone signaling supports tissue repair processes. A well-established combination in recovery protocols.
Molecular Data
CJC-1295 (without DAC) GHK-Cu
Weight 3,367.97 Da 404.96 Da
Half-life 30 minutes - 2 hours 0.5-2 hours
Chain 30 amino acids 3 amino acids
Type GHRH analog Copper tripeptide
Key Benefits
CJC-1295 (without DAC)
01 Preserves natural GH pulsatility
02 Minimal side effects
03 No receptor desensitization
04 Precise GH release control
05 4x greater receptor affinity than native GHRH
GHK-Cu
01 Enhanced collagen production (70% increase in type I and III)
02 Improved skin elasticity
03 Reduced fine lines and wrinkles
04 Accelerated wound healing
05 Hair growth stimulation
06 Antioxidant protection
Dosing Protocols
CJC-1295 (without DAC)
100-300mcg per injection / 2-3 times daily (morning, post-workout optional, bedtime)
Anti-Aging/Wellness 100mcg 2x daily (morning and bedtime)
Body Composition 100-150mcg 3x daily (morning, post-workout, bedtime)
Maximum GH Release 200mcg 2-3x daily with GHRP
Sleep Enhancement 100-200mcg Once at bedtime
GHK-Cu
0.5-2% topical or 1-3mg injectable / 1-2x daily
Systemic anti-aging 1-2mg 1x daily
Enhanced regeneration 2-3mg 1-2x daily
Side Effects
CJC-1295 (without DAC)
Generally well-tolerated at recommended doses
Temporary facial flushing/warmth (5-10 minutes post-injection)
GHK-Cu
Mild skin irritation initially (usually resolves)
Increased photosensitivity
Contraindications
Active cancer (due to growth-promoting effects)
Diabetic retinopathy
Severe kidney disease
Pregnancy or breastfeeding
Known copper sensitivity or Wilson's disease
Active skin infections at application site
Pregnancy or breastfeeding (injectable)
Research Evidence
CJC-1295 (without DAC) GHK-Cu
Status Well Studied Well Studied
References 5 studies 5 studies
Latest November 2024 July 2025
FDA Approved No No
This comparison is for educational and research purposes only. Consult a healthcare professional before use.