IGF-1 LR3 vs TB-500
limited vs Well Studied
synergistic Different repair pathway activation.
Molecular Data
IGF-1 LR3 TB-500
Weight — 4,963.44 Da
Half-life 20-30 hours ~2 hours
Chain 83 amino acids 43 amino acids
Type Synthetic IGF-1 analog Thymosin fragment
Key Benefits
IGF-1 LR3
01 Approximately 3x more potent than native IGF-1
02 Promotes muscle hypertrophy and hyperplasia in animal models
03 15-20% lean mass gains observed in 4-week rat studies
04 Anti-catabolic effects preserve muscle during cachexia
05 20-30 hour half-life for sustained effects
TB-500
01 Superior systemic tissue repair
02 Accelerated muscle, tendon, and ligament healing
03 Enhanced cell migration and angiogenesis
04 Comprehensive regenerative effects
05 Neuroprotective properties
Dosing Protocols
IGF-1 LR3
20-100 mcg daily (start low at 20-30 mcg) / Once daily, or split AM/PM for higher doses
Beginner Protocol 20-30mcg Once daily post-workout
Intermediate 40-60mcg Once daily
Advanced 80-100mcg Once or split AM/PM
Women's Protocol 10-20mcg Once daily
TB-500
2-5mg per injection (higher doses for serious injuries) / 2-3x weekly (e.g., Monday, Wednesday, Friday)
General tissue repair 2-3mg 2x weekly
Serious injury recovery 4-5mg 3x weekly
Athletic enhancement 2-3mg 2x weekly
Chronic conditions 3-4mg 2-3x weekly
Maintenance 2mg 1-2x weekly
Post-surgical recovery 3-5mg 3x weekly
Side Effects
IGF-1 LR3
Hypoglycemia (lasting up to 30 hours) - CRITICAL
Water retention
Joint stiffness
Muscle soreness
Increased pump during workouts
TB-500
Generally minimal side effects
Possible mild injection site reactions
Temporary fatigue in some users
Contraindications
NEVER approved for human use - research chemical only
Cancer history or undiagnosed growths
May cause organ hypertrophy (heart, intestines)
WADA prohibited - causes failed drug tests
Active cancer treatment (due to angiogenic effects)
Pregnancy or breastfeeding
Immunosuppressive medications (consult provider)
WADA prohibited for competitive athletes
Research Evidence
IGF-1 LR3 TB-500
Status limited Well Studied
References 4 studies 4 studies
Latest — March 2024
FDA Approved No No
This comparison is for educational and research purposes only. Consult a healthcare professional before use.