Interaction Checker
Add peptides or compounds to check all pairwise interactions, cumulative organ load, and safety flags.
Cumulative Organ Load
Shared Safety Flags
A testosterone base is essential when running DHB. DHB suppresses endogenous testosterone production and does not aromatize, so without exogenous testosterone, estradiol levels will crash, leading to low-estrogen symptoms including joint pain, flat mood, low libido, and adverse lipid changes. Typical ratios are 1:4 to 1:2 DHB-to-testosterone (e.g., 200-400 mg DHB with 500-800 mg testosterone per week). The testosterone provides the estrogenic support that DHB cannot.
Interaction data is compiled from research literature, pharmacological analysis, and community reports. Inferred interactions are based on known mechanisms and may not reflect all real-world outcomes. Always consult a healthcare professional before combining compounds.