AHK-Cu vs GHK-Cu
Well Studied vs Well Studied
synergistic Complementary copper peptides targeting different aspects of tissue regeneration. GHK-Cu excels at skin repair while AHK-Cu targets hair follicles.
Molecular Data
AHK-Cu GHK-Cu
Weight 416.9 Da 404.96 Da
Half-life Not established 0.5-2 hours
Chain 3 amino acids 3 amino acids
Type Copper tripeptide complex Copper tripeptide
Key Benefits
AHK-Cu
01 Hair follicle elongation stimulation
02 Dermal papilla cell proliferation
03 VEGF upregulation for improved scalp circulation
04 TGF-β1 reduction (counters DHT effects)
05 Anti-apoptotic protection for follicles
06 Collagen synthesis support
07 Convenient topical application
08 Fibroblast activation for skin regeneration
GHK-Cu
01 Enhanced collagen production (70% increase in type I and III)
02 Improved skin elasticity
03 Reduced fine lines and wrinkles
04 Accelerated wound healing
05 Hair growth stimulation
06 Antioxidant protection
Dosing Protocols
AHK-Cu
0.5-1% topical solution/serum / Once or twice daily application
Mesotherapy - Scalp (Practitioner) 0.1-0.5 mg per injection site Weekly sessions
Research Protocol 1-5 mg 2-3 times weekly
GHK-Cu
0.5-2% topical or 1-3mg injectable / 1-2x daily
Systemic anti-aging 1-2mg 1x daily
Enhanced regeneration 2-3mg 1-2x daily
Side Effects
AHK-Cu
Generally well-tolerated with excellent safety profile in topical applications
Rare scalp irritation (patch test recommended)
Potential for mild redness on sensitive skin
GHK-Cu
Mild skin irritation initially (usually resolves)
Increased photosensitivity
Contraindications
Not for use on broken or infected skin
Avoid eye area - may cause irritation
Do not use if allergic to copper or peptides
Not recommended during acute skin infections
Known copper sensitivity or Wilson's disease
Active skin infections at application site
Pregnancy or breastfeeding (injectable)
Research Evidence
AHK-Cu GHK-Cu
Status Well Studied Well Studied
References 4 studies 3 studies
FDA Approved No No
This comparison is for educational and research purposes only. Consult a healthcare professional before use.