Dihexa vs Selank
Emerging vs Well Studied
compatible Synergistic effects; watch for neural overstimulation.
Molecular Data
Dihexa Selank
Weight 504.7 Da 751.89 Da
Half-life 8-12 days 2-10 minutes
Chain — 7 amino acids
Type Modified oligopeptide Tuftsin analog
Key Benefits
Dihexa
01 Dramatic synaptogenesis promotion
02 10 million times more potent than BDNF
03 Cognitive enhancement and memory improvement
04 Neuroprotection and potential neuroregeneration
05 Applications for Alzheimer's, TBI, age-related cognitive decline
06 Oral bioavailability
Selank
01 Rapid onset anxiolytic effects
02 Enhanced BDNF expression (30% increase)
03 Improved stress resilience
04 Cognitive enhancement
05 Immune modulation
06 No tolerance or withdrawal
07 Neuroprotective effects
Dosing Protocols
Dihexa
8-10mg oral or 2-5mg injectable (0.5mg/kg based on research) / Once daily in the morning
Research protocol 0.5mg/kg daily Daily or 3x weekly
Standard injectable 2-5mg total 1x daily
Selank
250-500mcg per dose / 1-2x daily (morning and/or evening)
Mild anxiety relief 250mcg 1x daily
Moderate anxiety/cognitive 250mcg 2x daily (morning & evening)
Intensive anxiety support 500mcg 1x daily (divided doses)
Cognitive enhancement 250-350mcg 1x daily (morning)
PTSD support 250mcg 2x daily
Immune support 250mcg 1x daily for 2-4 weeks
Side Effects
Dihexa
Headaches (most frequent side effect)
Anxiety or overstimulation
Sleep disruption when dosed late in day
Mental clarity increase
Selank
Minimal side effects - excellent safety profile
No sedation or cognitive impairment
No tolerance, dependence, or withdrawal
Contraindications
Not FDA approved - research compound only
Theoretical cancer risk via c-Met activation
Cancer history (avoid due to c-Met pathway)
Pregnancy or breastfeeding
No long-term human safety data
Known peptide allergies
Pregnancy or breastfeeding
Consult healthcare provider with multiple psychiatric medications
Research Evidence
Dihexa Selank
Status Emerging Well Studied
References 3 studies 4 studies
Latest 2024 March 2024
FDA Approved No No
This comparison is for educational and research purposes only. Consult a healthcare professional before use.