Phenylpiracetam vs Selank
Moderate Research vs Well Studied
compatible Researched · 90% Balanced anxiety relief and cognition enhancement.
Molecular Data
Phenylpiracetam Selank
Weight 218.25 Da 751.89 Da
Half-life ~3-5 hours 2-10 minutes
Chain — 7 amino acids
Type Racetam derivative (C12H14N2O2) Tuftsin analog
Key Benefits
Phenylpiracetam
01 Potent cognitive enhancement including improved memory, focus, and information processing speed
02 Psychostimulant properties that increase motivation, mental energy, and alertness without the jitteriness of classical stimulants
03 Physical performance enhancement through improved stamina, reduced perception of effort, and increased exercise tolerance
04 Enhanced cold tolerance -- a unique property among nootropics, originally developed for extreme-environment performance
05 Anxiolytic effects at standard doses, reducing stress reactivity without sedation
06 Anticonvulsant activity demonstrated in preclinical models
Selank
01 Rapid onset anxiolytic effects
02 Enhanced BDNF expression (30% increase)
03 Improved stress resilience
04 Cognitive enhancement
05 Immune modulation
06 No tolerance or withdrawal
07 Neuroprotective effects
Dosing Protocols
Phenylpiracetam
100-200 mg, 1-2x/day / Once or twice daily (morning, or morning and early afternoon)
Selank
250-500mcg per dose / 1-2x daily (morning and/or evening)
Mild anxiety relief 250mcg 1x daily
Moderate anxiety/cognitive 250mcg 2x daily (morning & evening)
Intensive anxiety support 500mcg 1x daily (divided doses)
Cognitive enhancement 250-350mcg 1x daily (morning)
PTSD support 250mcg 2x daily
Immune support 250mcg 1x daily for 2-4 weeks
Side Effects
Phenylpiracetam
Insomnia, particularly if taken in the afternoon or evening -- the stimulant effects can persist for several hours after dosing
Irritability and overstimulation, especially at higher doses or when combined with other stimulants
Headache, most commonly caused by increased acetylcholine demand without adequate choline supplementation
Rapid tolerance development -- the most significant practical limitation, requiring intermittent dosing schedules to maintain efficacy
Selank
Minimal side effects - excellent safety profile
No sedation or cognitive impairment
No tolerance, dependence, or withdrawal
Contraindications
Known hypersensitivity to phenylpiracetam or other racetams
Severe hypertension or cardiovascular disease (due to stimulant properties)
Pregnancy and breastfeeding (insufficient safety data)
Severe hepatic or renal impairment
Competitive athletes subject to WADA testing (phenylpiracetam is a prohibited substance under Section S6: Stimulants)
Known peptide allergies
Pregnancy or breastfeeding
Consult healthcare provider with multiple psychiatric medications
Research Evidence
Phenylpiracetam Selank
Status Moderate Research Well Studied
References 5 studies 5 studies
Latest — 2020
FDA Approved No No
This comparison is for educational and research purposes only. Consult a healthcare professional before use.