Selank vs Semax
Well Studied vs Well Studied
synergistic Enhanced cognitive and anxiolytic effects when combined.
Molecular Data
Selank Semax
Weight 751.89 Da 813.93 Da
Half-life 2-10 minutes 0.5-2 hours
Chain 7 amino acids 7 amino acids
Type Tuftsin analog ACTH(4-10) synthetic analog
Key Benefits
Selank
01 Rapid onset anxiolytic effects
02 Enhanced BDNF expression (30% increase)
03 Improved stress resilience
04 Cognitive enhancement
05 Immune modulation
06 No tolerance or withdrawal
07 Neuroprotective effects
Semax
01 Rapid brain delivery via intranasal route
02 Rapidly increases BDNF levels
03 Extensive clinical research in Russia
04 Easy self-administration
05 Modulates dopamine and serotonin systems
06 Neuroprotective effects
Dosing Protocols
Selank
250-500mcg per dose / 1-2x daily (morning and/or evening)
Mild anxiety relief 250mcg 1x daily
Moderate anxiety/cognitive 250mcg 2x daily (morning & evening)
Intensive anxiety support 500mcg 1x daily (divided doses)
Cognitive enhancement 250-350mcg 1x daily (morning)
PTSD support 250mcg 2x daily
Immune support 250mcg 1x daily for 2-4 weeks
Semax
300-600mcg per dose (up to 1000mcg for intensive use) / 1-2x daily (morning recommended for cognitive boost)
Research protocol 500-750mcg 1x daily
Intensive protocol 750-1000mcg 1-2x daily
Side Effects
Selank
Minimal side effects - excellent safety profile
No sedation or cognitive impairment
No tolerance, dependence, or withdrawal
Semax
Mild nasal discomfort (nasal route)
Possible nasal sensation upon administration
Contraindications
Known peptide allergies
Pregnancy or breastfeeding
Consult healthcare provider with multiple psychiatric medications
Pregnancy or breastfeeding
Known peptide allergies
Do not exceed 4-week continuous use without medical supervision
Research Evidence
Selank Semax
Status Well Studied Well Studied
References 4 studies 4 studies
Latest March 2024 2021
FDA Approved No No
This comparison is for educational and research purposes only. Consult a healthcare professional before use.