Hexarelin vs TB-500
Well Studied vs Well Studied
synergistic Mechanism-based · 47% Hexarelin and TB-500 work through complementary pathways. Growth hormone signaling supports tissue repair processes. A well-established combination in recovery protocols.
Molecular Data
Hexarelin TB-500
Weight 887 Da 4,963.44 Da
Half-life 1-2 hours ~2 hours
Chain 6 amino acids 43 amino acids
Type Synthetic hexapeptide Thymosin fragment
Key Benefits
Hexarelin
01 Most potent GHRP for GH stimulation
02 Powerful synergy with GHRH peptides
03 Cardioprotective effects via CD36 receptor
04 Enhanced muscle growth and strength
05 Improved fat metabolism
06 Better recovery and tissue repair
07 Maintains natural GH pulsatility
08 Stable against proteolytic enzymes
TB-500
01 Superior systemic tissue repair
02 Accelerated muscle, tendon, and ligament healing
03 Enhanced cell migration and angiogenesis
04 Comprehensive regenerative effects
05 Neuroprotective properties
Dosing Protocols
Hexarelin
100-200 mcg per injection / 2-3 times daily for optimal GH pulses
GH optimization 100 mcg 2-3x daily
Enhanced results 200 mcg 2-3x daily
With GHRH (synergy) 100 mcg each 2-3x daily
Cardioprotection 100-200 mcg 1-2x daily
TB-500
2-5mg per injection (higher doses for serious injuries) / 2-3x weekly (e.g., Monday, Wednesday, Friday)
General tissue repair 2-3mg 2x weekly
Serious injury recovery 4-5mg 3x weekly
Athletic enhancement 2-3mg 2x weekly
Chronic conditions 3-4mg 2-3x weekly
Maintenance 2mg 1-2x weekly
Post-surgical recovery 3-5mg 3x weekly
Side Effects
Hexarelin
Increased appetite (less than GHRP-6)
Water retention
Tingling or numbness
Tiredness after injection
Mild headache
TB-500
Generally minimal side effects
Possible mild injection site reactions
Temporary fatigue in some users
Contraindications
Active cancer or history of cancer
Pregnancy or breastfeeding
Pituitary disorders
WADA prohibited for competitive athletes
Active cancer treatment (due to angiogenic effects)
Pregnancy or breastfeeding
Immunosuppressive medications (consult provider)
WADA prohibited for competitive athletes
Research Evidence
Hexarelin TB-500
Status Well Studied Well Studied
References 4 studies 6 studies
Latest — November 2025
FDA Approved No No
This comparison is for educational and research purposes only. Consult a healthcare professional before use.