Dihexa vs NA-Selank Amidate
Emerging vs Moderate Research
compatible Different nootropic mechanisms; can be combined.
Molecular Data
Dihexa NA-Selank Amidate
Weight 504.7 Da 864 Da
Half-life 8-12 days 4-6 hours
Chain — 7 amino acids + modifications
Type Modified oligopeptide Modified heptapeptide
Key Benefits
Dihexa
01 Dramatic synaptogenesis promotion
02 10 million times more potent than BDNF
03 Cognitive enhancement and memory improvement
04 Neuroprotection and potential neuroregeneration
05 Applications for Alzheimer's, TBI, age-related cognitive decline
06 Oral bioavailability
NA-Selank Amidate
01 Pronounced anxiolytic effects without sedation
02 Enhanced blood-brain barrier penetration (vs standard Selank)
03 Improved metabolic stability and longer half-life
04 Nootropic effects with enhanced memory and learning
05 Increased BDNF levels for neuroplasticity
06 No dependency or withdrawal effects
07 Immune-modulating properties
08 Effects persist after treatment cessation
Dosing Protocols
Dihexa
8-10mg oral or 2-5mg injectable (0.5mg/kg based on research) / Once daily in the morning
Research protocol 0.5mg/kg daily Daily or 3x weekly
Standard injectable 2-5mg total 1x daily
NA-Selank Amidate
200-500mcg per administration / 1-2x daily for 14-20 days
Alternative delivery 250-500 mcg 1-2x daily
Side Effects
Dihexa
Headaches (most frequent side effect)
Anxiety or overstimulation
Sleep disruption when dosed late in day
Mental clarity increase
NA-Selank Amidate
Generally well-tolerated
Mild nasal irritation (intranasal)
Fatigue (rare)
Contraindications
Not FDA approved - research compound only
Theoretical cancer risk via c-Met activation
Cancer history (avoid due to c-Met pathway)
Pregnancy or breastfeeding
No long-term human safety data
Pregnancy or breastfeeding
Known hypersensitivity to Selank or tuftsin
Severe psychiatric conditions (consult professional)
Research Evidence
Dihexa NA-Selank Amidate
Status Emerging Moderate Research
References 3 studies 4 studies
Latest 2024 —
FDA Approved No No
This comparison is for educational and research purposes only. Consult a healthcare professional before use.