Best Compounds for Joint & Bone Health

Peptides studied for joint repair, cartilage regeneration, bone density, and osteoarthritis.

8 compounds ranked by research effectiveness

01

Abaloparatide

Extensively Studied

PTHrP Analog | Anabolic Bone-Building Agent

Postmenopausal Osteoporosis most effective
Male Osteoporosis most effective
Fracture Prevention most effective
Sequential Therapy effective
Half-life: ~1.7 hours
02

Teriparatide

Extensively Studied

PTH(1-34) | Bone-Building Anabolic Peptide

Postmenopausal Osteoporosis most effective
Male Osteoporosis most effective
Glucocorticoid-Induced Osteoporosis effective
Fracture Healing moderate
Dental Bone Regeneration moderate
Half-life: ~1 hour (subcutaneous); ~5 minutes (intravenous)
03

Raloxifene

FDA Approved

Selective Estrogen Receptor Modulator | Gynecomastia & Bone Health

Osteoporosis Prevention and Treatment most effective
Half-life: ~28 hours
04

Oxandrolone

Well Studied

Oral Anabolic Steroid | Lean Mass & Recovery

Osteoporosis-Related Bone Pain effective
Turner Syndrome Growth Support effective
Half-life: ~9-10 hours
05

AOD-9604

Well Studied

Modified hGH Fragment | Fat Loss Peptide

Cartilage Repair effective
Osteoarthritis Support moderate
Half-life: 3-4 minutes
06

Cartalax

Emerging

Bioregulatory Tripeptide | Cartilage & Connective Tissue Support

Osteoarthritis effective
Degenerative Joint Disease Prevention moderate
Post-Fracture Recovery moderate
Half-life: Minutes (short peptide); effects persist via epigenetic changes
07

MK-677

Well Studied

Ghrelin Receptor Agonist | Oral Growth Hormone Secretagogue

Bone Formation effective
Half-life: ~24 hours
08

MK-2866

Moderate Research

Selective Androgen Receptor Modulator | Muscle Wasting Research

Bone Mineral Density moderate
Half-life: ~24 hours

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