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Cartalax

Emerging

Bioregulatory Tripeptide | Cartilage & Connective Tissue Support

Dose 100-200mcg oral (1-2 capsules) or 700-1400mcg injectable
Frequency 1-2 times daily with meals (oral) or once daily (injectable)
Cycle 1-3 months depending on application
Storage Oral capsules: room temperature; Injectable lyophilized: 2-8°C; Reconstituted: 2-8°C refrigerated

Synthetic tripeptide developed by Professor Vladimir Khavinson, supporting cartilage, connective tissue, and cellular regeneration through proliferation markers and apoptosis pathway modulation.

Mechanism of Action

Modulates cell proliferation, suppresses apoptosis, affects fibroblast activity, reduces senescence markers, and influences extracellular matrix preservation.

Key Benefits

  • Joint and connective tissue support
  • Potential anti-aging effects on fibroblasts
  • Cartilage regeneration support
  • Established safety profile in Russian clinical practice
Molecular Weight
~350 Da
Chain Length
3 amino acids
Type
Tripeptide
Amino Acid Sequence
One-letter: AE?
H₂N
A 1
O C
N
E 2
O C
N
H
? 3
COOH
Ala
1

Alanine

Position 1

Glu
2

Glutamic Acid

Position 2

Asp
3

Asp (AED)

Position 3

N-terminus C-terminus
Hydrophobic
Polar
Positive (+)
Negative (-)
Modified

Joint Health

  • Osteoarthritis

    Clinical efficacy shown in osteochondrosis, osteoarthritis, and osteoporosis treatment.

  • Degenerative Joint Disease Prevention

    Supports cartilage maintenance and joint function.

  • Post-Fracture Recovery

    Supports bone and connective tissue healing.

Skin Health

  • Fibroblast Activation

    Increased Ki-67 expression with suppressed apoptosis in young and aged cells.

  • Collagen Production

    Enhances collagen synthesis in connective tissue.

  • Cellular Senescence Reduction

    Inhibited MMP-9 synthesis; maintained extracellular matrix integrity.

Capsule form; do not chew, swallow whole with water during meals.

GoalDoseFrequencyRoute
Joint Support100-200mcg (1-2 capsules)1-2x daily with mealsOral
Other Khavinson Peptides

Complementary bioregulatory effects across organ systems.

synergistic
Collagen Supplements

May enhance synthesis while supplements provide raw materials.

synergistic
BPC-157

Different mechanisms; no direct interaction.

compatible
TB-500

Distinct action pathways; may complement effects.

compatible
Growth Factors (IGF-1, GH)

Both affect tissue growth; monitor for excessive proliferation.

monitor
Glucosamine/Chondroitin

Complementary joint support mechanisms.

synergistic
Week 1-2

Establishing baseline; minimal noticeable changes

Week 3-4

Gradual improvement in joint comfort

Month 2

Noticeable mobility improvements

Month 3

Maximum therapeutic effect achieved

Common Side Effects

  • No reported side effects in Russian clinical use when taken properly
  • Well-tolerated in elderly patients

Stop Signs - Discontinue if:

  • Allergic reactions
  • Digestive upset (rare with proper administration)
  • No improvement after 3 months
  • Unexpected symptoms

Contraindications

  • Pregnancy and breastfeeding
  • Active cancer (theoretical proliferation risk)

Good Signs

  • Professional Russian packaging with holographic seals
  • Exactly 0.1mg (100mcg) AC-4 peptide complex per capsule
  • Clear Russian/English instructions specifying 'with meals'

Warning Signs

  • Proper documentation required for authenticity
  • Import verification needed

Bad Signs

  • Missing holographic seals or professional packaging
  • Unclear dosing instructions
  • Fibroblast Proliferation Study
    (2019)

    Human skin fibroblasts; 72 hours at 20 nM. Increased Ki-67 expression with suppressed apoptosis in young and aged cells.

  • Kidney Cell Culture Research
    (2020)

    Renal epithelial cells; 7 days. Reduced pro-apoptotic p53 expression in aging kidney cells.

  • Clinical Spine & Joint Study (Russia)
    (N/A)

    Human subjects; 1-3 months with 0.1mg capsules daily. Efficacy in osteochondrosis, osteoarthritis, and osteoporosis treatment.

  • Matrix Metalloproteinase Research
    (2020)

    Fibroblast cultures; 5 days at 20 nM. Inhibited MMP-9 synthesis; maintained extracellular matrix integrity.

Disclaimer

This information is for educational and research purposes only. Consult a healthcare professional before use.