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Cardiogen

Moderate Research

AEDR | Cardiovascular Bioregulator Peptide

Dose 10-20 mg daily
Frequency Once daily for 10-20 consecutive days
Cycle 10-20 days per cycle
Storage Capsules: room temperature; Injectable lyophilized: 2-8°C; Reconstituted: 2-8°C refrigerated

Cardiogen is a Khavinson bioregulator peptide consisting of four amino acids, derived from heart tissue research. Unlike larger peptides that work on cell surfaces, Cardiogen penetrates directly to the cell nucleus where it binds to specific DNA regions to regulate gene expression. This epigenetic mechanism supports tissue repair and improves cardiovascular function, particularly benefiting the heart and blood vessels.

Mechanism of Action

Cardiogen works through epigenetic regulation by penetrating cell nuclei and interacting with specific DNA regions, histones, and nucleosomes. It regulates which genes are activated or suppressed without changing DNA sequence. This mechanism supports cardiac tissue repair, enhances myocardial function, and improves cardiovascular tissue regeneration by influencing gene expression in heart cells.

Key Benefits

  • Supports cardiac tissue repair and regeneration
  • Regulates cardiovascular gene expression
  • Improves myocardial function
  • May support post-cardiac event recovery
  • Epigenetic mechanism for targeted action
  • Works at DNA/nuclear level
  • Part of comprehensive anti-aging protocols
  • Well-researched Khavinson peptide
Molecular Weight
460 Da
Chain Length
4 amino acids
Type
Tetrapeptide bioregulator
Amino Acid Sequence
One-letter: AEDR
H₂N
A 1
O C
N
E 2
O C
N
D 3
O C
N
R 4
COOH
Ala
1

Alanine

Position 1

Glu
2

Glutamic Acid

Position 2

Asp
3

Aspartic Acid

Position 3

Arg
4

Arginine

Position 4

N-terminus C-terminus
Hydrophobic
Polar
Positive (+)
Negative (-)
Modified

Cardiovascular Support

  • Cardiac Tissue Repair

    Supports heart tissue repair through gene expression regulation at the nuclear level.

  • Myocardial Function

    May improve overall myocardial function and cardiac performance.

  • Cardiovascular Aging

    Addresses age-related cardiovascular decline through bioregulation.

Anti-Aging

  • Epigenetic Regulation

    Influences gene expression to support tissue repair without altering DNA sequence.

  • Tissue Regeneration

    Promotes cardiac tissue regeneration at the cellular level.

Available in capsule form for oral administration. Short peptides can be absorbed orally and reach target tissues. Typical protocol involves 10-20 day cycles, often repeated 2-3 times per year.

GoalDoseFrequencyRoute
Standard protocol10-20 mgDaily for 10-20 daysOral capsules
Maintenance10 mg2-3 cycles yearlyOral capsules
Vesugen

Complementary cardiovascular bioregulators - Cardiogen for heart, Vesugen for vessels.

synergistic
Epitalon

Often combined in comprehensive anti-aging Khavinson protocols.

synergistic
Thymalin

Different organ targets; can be used in comprehensive bioregulator protocols.

compatible
Pinealon

Part of Khavinson bioregulator family; targets different tissue.

compatible
During cycle

Gene expression modulation begins

Post-cycle

Effects persist due to epigenetic changes

Months

Cardiovascular function improvements

Long-term

Cumulative benefits with periodic cycles

Common Side Effects

  • Generally well-tolerated
  • Minimal side effects reported

Stop Signs - Discontinue if:

  • Allergic reactions
  • Unusual cardiac symptoms

Contraindications

  • Active cardiac emergencies (seek medical care)
  • Known hypersensitivity
  • Pregnancy or breastfeeding

Good Signs

  • White powder or capsules
  • Clear solution if reconstituted
  • Proper packaging and labeling

Warning Signs

  • Unknown source or purity

Bad Signs

  • Discoloration
  • Unusual odor
  • Damaged packaging
  • Peptide Regulation of Gene Expression: A Systematic Review
    Molecules (MDPI) (2021)

    Short peptides can penetrate nuclei, interact with DNA and histones to regulate gene expression.

  • Cardiogen Bioregulator Research
    Bulletin of Experimental Biology and Medicine (2015)

    Demonstrated effects on cardiac tissue through gene expression modulation.

  • Khavinson Peptide Bioregulators Overview
    Advances in Gerontology (2020)

    Comprehensive review of bioregulator peptides and their epigenetic mechanisms.

Disclaimer

This information is for educational and research purposes only. Consult a healthcare professional before use.