NAD+
Essential Cellular Coenzyme & Anti-Aging Therapy
NAD+ is a crucial coenzyme found in every cell, involved in energy generation and cellular maintenance that naturally declines with age. Supplementation may support cellular health, boost energy, enhance cognitive function, and promote longevity through multiple delivery methods.
Mechanism of Action
Direct delivery to bloodstream ensures maximum cellular availability for energy production via ATP synthesis, DNA repair through PARP activation, and sirtuin-mediated longevity pathways. Supports mitochondrial function and metabolic homeostasis.
Key Benefits
- Restores mitochondrial function and ATP synthesis
- Enhances glucose and fat metabolism
- Improves oxygen utilization and endurance
- Activates DNA repair mechanisms
- Supports longevity pathways via sirtuins
- Improves mental clarity and focus
C21H27N7O14P2 Complex or non-standard sequence format
Energy & Metabolism
- Cellular Energy Production
Restores NAD+ levels for optimal ATP synthesis
- Metabolic Optimization
Enhances glucose and fat metabolism
- Exercise Performance
Improves oxygen utilization and endurance
Anti-Aging
- DNA Repair
Activates PARP enzymes for genomic stability
- Sirtuin Activation
Supports longevity pathways
- Cellular Senescence Reduction
May help clear senescent cells
Neurological
- Cognitive Enhancement
Improves mental clarity and focus
- Neuroprotection
Supports neuronal health and function
Highest bioavailability (100%) via IV, IM, or subcutaneous injection.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| IV Infusion | 250-1000mg | 1-2x weekly | Intravenous |
| IM/SubQ | 100-500mg | 2-3x weekly | Intramuscular or Subcutaneous |
Enhanced cellular repair and energy production
Complementary tissue regeneration effects
Supports metabolic pathways enhanced by GLP-1 agonists
Growth hormone pathways benefit from improved energy metabolism
Enhanced recovery and anti-aging effects
Alcohol significantly reduces NAD+ levels and effectiveness
Initial energy improvements and mental clarity
Enhanced physical performance and recovery
Sustained energy levels and improved sleep quality
Optimized metabolic function and cognitive benefits
Common Side Effects
- Mild flushing during IV infusion
- Temporary nausea
Stop Signs - Discontinue if:
- Severe injection site reactions or infection signs
- Persistent nausea or gastrointestinal distress
- Unusual fatigue or weakness
- Allergic reactions (rash, swelling, breathing difficulty)
Contraindications
- IV administration requires medical supervision
- Avoid alcohol during treatment
- Maintain consistent dosing schedule
Good Signs
- Clear, colorless solution (injectable)
- Proper refrigeration at 2-8°C
- Sterile injection technique
- Third-party tested for purity
Warning Signs
- Use reconstituted solution within 28 days
Bad Signs
- Cloudy or discolored solution indicates contamination
- Room temperature storage degrades NAD+ rapidly
- NAD+ Restoration Strategies in Clinical PracticeRegenerative Medicine Journal (2024)
Review of clinical applications and restoration strategies
- Clinical Evidence for NAD+ Therapeutic ApplicationsClinical Interventions in Aging (2024)
Evidence for anti-aging and therapeutic applications
- NAD+ Precursor Safety and Efficacy Meta-AnalysisNature Metabolism (2024)
Meta-analysis of safety and efficacy data
- Intranasal NAD+ Delivery for Neurological ApplicationsNeuropharmacology Research (2023)
Demonstrated efficacy of intranasal delivery for brain access
Disclaimer
This information is for educational and research purposes only. Consult a healthcare professional before use.