BPC-157
Body Protection Compound-157 | Pentadecapeptide
Synthetic peptide derived from gastric juice protein, renowned for tissue repair, inflammation reduction, and GI protection capabilities. BPC-157 promotes blood vessel formation, enhances collagen synthesis, modulates growth factor expression, and protects against tissue damage through localized or systemic delivery.
Mechanism of Action
Promotes blood vessel formation (angiogenesis), enhances collagen synthesis, modulates growth factor expression including VEGF, and protects against tissue damage through localized or systemic delivery pathways.
Key Benefits
- Accelerated tendon, ligament, muscle, and bone healing
- Localized tissue repair with direct targeting
- Superior bioavailability
- Anti-inflammatory effects
- Angiogenesis promotion
- Gastric and intestinal protection
GKPPPGKPADDAGLVGlycine
Position 1
Lysine
Position 2
Proline
Position 3
Proline
Position 4
Proline
Position 5
Glycine
Position 6
Lysine
Position 7
Proline
Position 8
Alanine
Position 9
Aspartic Acid
Position 10
Aspartic Acid
Position 11
Alanine
Position 12
Glycine
Position 13
Leucine
Position 14
Valine
Position 15
Wound Healing
- Tendon Healing
Accelerated tendon-to-bone healing with improved biomechanical properties; most effective with localized injection.
- Muscle Recovery
Enhanced healing and reduced recovery following crush injuries and surgical procedures with direct tissue targeting.
- Angiogenesis
Promotes blood vessel formation and improves vascularization through localized delivery.
Neurological
- Neuroprotection
Protective effects against neurotoxic agents and ischemic brain injury models.
- Spinal Cord Injury
Improved functional recovery and reduced tissue damage in spinal cord injury studies.
- Peripheral Nerves
Enhanced peripheral nerve regeneration and functional recovery after injury.
Gastrointestinal
- Ulcer Protection
Protective effects against gastric and duodenal ulcers through cytoprotective mechanisms.
- Intestinal Repair
Acceleration of intestinal healing with reduced inflammatory markers in IBD models.
- Mucosal Healing
Enhanced mucosal barrier function and accelerated epithelial regeneration.
Most effective for localized healing when injected near injury site. Subcutaneous injection preferred for targeted tissue repair.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Tendon/Joint healing | 250-500 mcg | 1-2x daily | SubQ near injury |
| Serious injury | 500-1000 mcg | 2x daily | SubQ near injury |
| General healing | 250-500 mcg | 1-2x daily | SubQ or IM |
| Maintenance | 250 mcg | 1x daily | SubQ |
Reconstitution Instructions
- Bacteriostatic water (BAC)
- Insulin syringes (0.5-1 mL)
- Alcohol swabs
- Peptide vial
- Sterile work surface
- 1 Clean work area and hands thoroughly
- 2 Calculate required BAC water volume using calculator
- 3 Draw BAC water into syringe
- 4 Inject slowly down vial side (not directly onto powder)
- 5 Gently swirl until dissolved (never shake)
- 6 Store in refrigerator, use within 28 days
Complementary healing mechanisms; often used together in the Wolverine Stack.
No known negative interactions.
BPC-157 increases GH receptor expression, amplifying growth hormone benefits.
BPC-157 upregulates GH receptors, enhancing effectiveness for tissue repair.
No known interactions; different mechanisms and receptor targets.
Safe combination; different pathways. Often combined in regenerative protocols.
Reduced inflammation and pain at injection site
Improved healing rate and tissue repair
Maximum localized healing benefits
Common Side Effects
- Mild injection site redness
- Injection site irritation
- Possible mild digestive adjustment (oral)
Stop Signs - Discontinue if:
- Persistent injection site reactions or infection signs
- Unusual swelling or rash around injection area
- Severe headaches or dizziness
- Allergic reactions
- Persistent or worsening digestive issues
Contraindications
- Active cancer (due to angiogenic effects)
- Pregnancy or breastfeeding
- Blood thinners (consult doctor due to angiogenesis)
- WADA prohibited for competitive athletes
Good Signs
- White, fluffy lyophilized powder (cake) filling vial bottom
- Crystal clear solution after reconstitution with no particles
- Intact vacuum seal on vial
Warning Signs
- Slight clumping that dissolves with gentle swirling (acceptable from shipping)
Bad Signs
- Collapsed, melted, or powder stuck to vial sides (heat exposure)
- Cloudy solution, particles, or precipitates after reconstitution
- Discoloration of powder
- Achilles Tendon Healing Study(2003)
Superior tendon healing with improved biomechanical properties and enhanced tendon-to-bone integration in rat models.
- Muscle Healing Research(2006)
Accelerated quadriceps healing with improved histology, reduced inflammation, and restored function in rat models.
- Spinal Cord Injury Recovery(2019)
Significant functional recovery, reduced tissue damage, and improved neurological outcomes in rat models.
- Gastric Ulcer Protection(2020)
Cytoprotective effects against gastric ulcers through multiple protective mechanisms.
- VEGF and Angiogenesis Study(2017)
Pro-angiogenic effects via VEGFR2 activation, explaining wound healing mechanisms.
- Safety Evaluation Study(2020)
No serious adverse effects at therapeutic doses up to 1000 μg/kg for 90 days; established safety profile.
Disclaimer
This information is for educational and research purposes only. Consult a healthcare professional before use.